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Chemical Structure : FABP4/5 inhibitor compound 3
Catalog No.: PC-38573Not For Human Use, Lab Use Only.
FABP4/5 inhibitor compound 3 is a potent dual FABP4 and FABP5 inhibitor with Kd of 0.02 and 0.56 uM, respectively.
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FABP4/5 inhibitor compound 3 is a potent dual FABP4 and FABP5 inhibitor with Kd of 0.02 and 0.56 uM, respectively.
FABP4/5 inhibitor compound 3 inhibited basal or isoproterenol-stimulated lipolysis in 3T3-L1 and primary human adipocytes.
FABP4/5 inhibitor compound 3 inhibited basal and LPS-stimulated MCP-1 release from THP-1 cells and primary human macrophages.
FABP4/5 inhibitor compound 3 ameliorated dyslipidemia but not insulin resistance in DIO mice.
| M.Wt | 427.285 | |
| Formula | C21H16Cl2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hong Lan, et al. J Lipid Res. 2011 Apr;52(4):646-56.
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