FABP inhibitor MF6 | FABP5/FABP7 inhibitor

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Chemical Structure : FABP inhibitor MF6

FABP inhibitor MF6 (FABP ligand 6)

Catalog No.: PC-25492Not For Human Use, Lab Use Only.

FABP inhibitor MF6 (FABP ligand 6) is a small molecule ligand / inhibitor of fatty acid-binding proteins (FABPs) with high affinity for FABP7 (Kd=20 nM), with much weaker affinity for FABP3 (Kd=1038 nM) and FABP5 (Kd=874 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	492.98
Formula	C28H26ClFN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-(5-(2-chlorophenyl)-1-(4-isopropylphenyl)-1H-pyrazol-3-yl)-4-fluorophenoxy)butanoic acid

References

1. Guo Q, et al. Biomedicines. 2021 May 10;9(5):529.

2. Cheng A., et al. Acta Pharmacol. Sin. 2021;0:1–11.

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FABP inhibitor MF6 (FABP ligand 6)

Biological Activity

Physicochemical Properties

References

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