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FAP-2286

Chemical Structure : FAP-2286

CAS No.: 2581741-18-4

FAP-2286 (Rofapitide tetraxetan)

Catalog No.: PC-26886Not For Human Use, Lab Use Only.

Rofapitide tetraxetan (FAP-2286) is a highly potent and selective Fibroblast activation protein (FAP)-binding peptide with a mean IC50 value of 2.7 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Rofapitide tetraxetan (FAP-2286) is a highly potent and selective Fibroblast activation protein (FAP)-binding peptide with a mean IC50 value of 2.7 nM.

Physicochemical Properties

M.Wt 1470.77
Formula C67H99N13O18S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,2',2''-(10-(2-((2-((((12S,32S,5R,13R,16S,19S,22S)-19-(3-Amino-3-oxopropyl)-16-benzyl-13-carboxy-5-hexanamido-22-((R)-1-hydroxyethyl)-2,4,15,18,21,24-hexaoxo-7,11-dithia-14,17,20,23-tetraaza-1(1,2),3(2,1)-dipyrrolidina-9(1,3)-benzenacyclotetracosaphane-95-yl)methyl)thio)ethyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid

References

1. Baum RP, et al. J Nucl Med. 2022 Mar;63(3):415-423.

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