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Chemical Structure : FAUC 1036
Catalog No.: PC-61170Not For Human Use, Lab Use Only.
FAUC 1036 is a potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.
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FAUC 1036 is a potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.
| M.Wt | 744.933 | |
| Formula | C45H52N4O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.
2. Milanos L, et al. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15277-15281.
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