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Chemical Structure : FAUC 1104
Catalog No.: PC-61171Not For Human Use, Lab Use Only.
FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.
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FAUC 1104 is a potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.
| M.Wt | 774.959 | |
| Formula | C46H54N4O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Milanos L, et al. J Med Chem. 2016 Mar 10;59(5):2222-43.
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