You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-HIV-FD028
FD028

Chemical Structure : FD028

CAS No.: 2563903-40-0

FD028 (FD-028, FD 028)

Catalog No.: PC-73248Not For Human Use, Lab Use Only.

FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.

Packing Price Stock Quantity
25 mg Get quote
100 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.
FD028 is not significantly toxic and has broad-spectrum HIV-1 inhibitory and inactivation activity, including T20-resistant viruses and T2635-resistant viruses.

Physicochemical Properties

M.Wt 881.812
Formula C42H39Cl2FN4O8S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-2-chloro-5-(5-((3-(4-(2-(4-(2-((4-chloro-3-fluorophenyl)amino)-2-oxoacetamido)-2,2,6,6-tetramethylpiperidin-1-yl)-2-oxoethoxy)phenethyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid

References

1. Jing Pu, et al. Front Pharmacol. 2021 Jan 25;11:613361. doi: 10.3389/fphar.2020.613361.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: