FGFR2/3 inhibitor 29

Chemical Structure : FGFR2/3 inhibitor 29

Catalog No.: PC-49450Not For Human Use, Lab Use Only.

FGFR2/3 inhibitor 29 is a potent and selective inhibitor of wild-type and gatekeeper mutant with IC50 of 0.5 nM (FGFR3).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FGFR2/3 inhibitor 29 is a potent and selective inhibitor of wild-type and gatekeeper mutant with IC50 of 0.5 nM (FGFR3).

M.Wt	450.517
Formula	C23H22D3N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-(6-(1-isopropyl-1H-pyrazol-4-yl)-5-((tetrahydrofuran-3-yl)oxy)pyrazolo[1,5-a]pyrimidin-3-yl)-N-(methyl-d3)nicotinamide

1. Shvartsbart A, et al. J Med Chem. 2022 Nov 10. doi: 10.1021/acs.jmedchem.2c01366.