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FGFR4-IN-1

Chemical Structure : FGFR4-IN-1

CAS No.: 1708971-72-5

FGFR4-IN-1

Catalog No.: PC-42217Not For Human Use, Lab Use Only.

A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM.

Physicochemical Properties

M.Wt 493.5151
Formula C24H27N7O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 6.4 mg/mL (Need warming)

Chemical Name/SMILES

1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(3-oxo-4-morpholinyl)methyl]-

References

1. Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO 2015059668 A1

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