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Chemical Structure : FGIN-1-27
Catalog No.: PC-72081Not For Human Use, Lab Use Only.
FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO).
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FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO).
FGIN-1-27 inhibited Th17 cell differentiation, significantly downregulated the expression of RORγt target genes, notably Il17a, Il17f, Il23r, Ltb4r1,Ccr6.
FGIN-1-27 protected mice against EAE, induced amino acid starvation response (AAR), FGIN-1-27 produced anti-anxiety and anti-panic effects in non-mammalian models.
| M.Wt | 436.615 | |
| Formula | C28H37FN2O | |
| Appearance | Solid | |
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1. Lima-Maximino MG, et al. Pharmacol Biochem Behav. 2018 Aug;171:66-73.
2. Singh A, et al. Sci Rep. 2020 Feb 28;10(1):3766.
3. Musicki B, et al. J Cell Physiol. 2021 Apr;236(4):3073-3082.
4. Rosenberg N, et al. Exp Clin Endocrinol Diabetes. 2018 Feb;126(2):77-84.
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