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FIM1033

Chemical Structure : FIM1033

CAS No.: 2018335-58-3

FIM1033 (FIM-1033)

Catalog No.: PC-72410Not For Human Use, Lab Use Only.

FIM1033 (FIM-1033) is a potent small-molecule inhibitor of FimH with HAI EC90 of 8 nM, with antibiotica activities, significantly attenuated bacterial loads in pyelonephritis in treated mice.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FIM1033 (FIM-1033) is a potent small-molecule inhibitor of FimH with HAI EC90 of 8 nM, with antibiotica activities, significantly attenuated bacterial loads in pyelonephritis in treated mice.

Physicochemical Properties

M.Wt 429.469
Formula C23H27NO7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Lisa K McLellan, et al. PLoS Pathog. 2021 Jan 29;17(1):e1009314.

2. Laurel Mydock-McGrane, et al. J Med Chem. 2016 Oct 27;59(20):9390-9408.

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