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FMAU

Chemical Structure : FMAU

CAS No.: 69256-17-3

FMAU (D-FMAU)

Catalog No.: PC-28207Not For Human Use, Lab Use Only.

FMAU (D-FMAU) is a deoxythymidine nucleoside analog inhibiting herpes simplex virus, various cancers, hepatitis B virus, and Epstein-Barr virus, shows broad-spectrum anti-orthopoxvirus activity with EC50 of 1.99 uM and 30 nM for vaccinia virus (VACV) and monkeypox virus (MPXV) respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

FMAU (D-FMAU) is a deoxythymidine nucleoside analog inhibiting herpes simplex virus, various cancers, hepatitis B virus, and Epstein-Barr virus, shows broad-spectrum anti-orthopoxvirus activity with EC50 of 1.99 uM and 30 nM for vaccinia virus (VACV) and monkeypox virus (MPXV) respectively.

Physicochemical Properties

M.Wt 260.22
Formula C10H13FN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

References

1. Zheng T, et al. Emerg Microbes Infect. 2026 Sep 15:2735153.

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