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FPR2 inhibitor (S)-11l

Chemical Structure : FPR2 inhibitor (S)-11l

CAS No.:

FPR2 inhibitor (S)-11l

Catalog No.: PC-72355Not For Human Use, Lab Use Only.

FPR2 inhibitor (S)-11l is a potent, selective, brain penetrant FPR2 agonist with IC50 of 0.13 uM (hFPR2).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FPR2 inhibitor (S)-11l is a potent, selective, brain penetrant FPR2 agonist with IC50 of 0.13 uM (hFPR2).

Physicochemical Properties

M.Wt 446.458
Formula C25H20F2N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

Chemical Name/SMILES

(S)-1-(3-(4-cyanophenyl)-1-(5-fluoroindolin-1-yl)-1-oxopropan-2-yl)-3-(4-fluorophenyl)urea

References

1. Margherita Mastromarino, et al. J Med Chem. 2022 Mar 24;65(6):5004-5028.

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