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FT108

Chemical Structure : FT108

CAS No.: 2379645-28-8

FT108 (FT-108)

Catalog No.: PC-72096Not For Human Use, Lab Use Only.

FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM).

    Physicochemical Properties

    M.Wt 320.345
    Formula C16H20N2O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-hydroxy-4-(tetrahydro-2H-pyran-4-carbonyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-8-carboxamide

    References

    1. Lanzhu Yue, et al. Blood. 2020 Jan 16;135(3):191-207.

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