FTO inhibitor F97

You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Histone Demethylase-FTO inhibitor F97

Chemical Structure : FTO inhibitor F97

Catalog No.: PC-24469Not For Human Use, Lab Use Only.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

F97 is a specific small molecule inhibitor of fat mass and obesity-associated protein (FTO) with IC50 of 0.45 uM, selectively inhibits m6A demethylation by FTO rather than ALKBH5, and has minimal effect on m1A demethylation by ALKBH3.
F97 increases the protein levels of RARA and ASB2, while decreasing that of MYC in AML cell lines.
F97exhibits antileukemia activity in a xenograft mice model without significant side-effects.

Physicochemical Properties

M.Wt	393.51
Formula	C22H23N3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((2,6-dicyclopropyl-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl)amino)thiophene-2-carboxylic acid

References

1. Deyan Zhang, et al. Eur J Med Chem. 2025 Feb 25:289:117444.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com