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Chemical Structure : Fadrozole
Catalog No.: PC-60698Not For Human Use, Lab Use Only.
A potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.
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A potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide; lowers ovarian estrogen synthesis by gonadotropin-primed, androstenedione treated mice, suppresses hormone-dependent and -independent tumors in vivo.
Breast Cancer
Approved
| M.Wt | 223.279 | |
| Formula | C14H13N3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Steele RE, et al. Steroids. 1987 Jul-Sep;50(1-3):147-61.
2. Schieweck K, et al. Cancer Res. 1988 Feb 15;48(4):834-8.
3. Juniewicz PE, et al. J Urol. 1988 Apr;139(4):827-31.
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