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Fesoterodine fumarate

Chemical Structure : Fesoterodine fumarate

CAS No.: 286930-03-8

Fesoterodine fumarate (PF-00695838 fumarate, SPM907, SPM-907)

Catalog No.: PC-61893Not For Human Use, Lab Use Only.

Fesoterodine fumarate (PF-00695838) is a competitive muscarinic receptor antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fesoterodine fumarate (PF-00695838) is a competitive muscarinic receptor antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors.
Fesoterodine has muscle relaxant and urinary antispasmodic properties.
Fesoterodine binds and inhibits muscarinic receptors on the bladder detrusor muscle, prevents bladder contractions or spasms caused by acetylcholine.

Physicochemical Properties

M.Wt 527.658
Formula C30H41NO7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate fumarate

References

1. Ney P, et al. BJU Int. 2008 Apr;101(8):1036-42.

2. Michel MC. Expert Opin Pharmacother. 2008 Jul;9(10):1787-96.

3. Chapple CR, et al. BJU Int. 2008 Nov;102(9):1128-32.

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