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Flubendazole

Chemical Structure : Flubendazole

CAS No.: 31430-15-6

Flubendazole

Catalog No.: PC-26069Not For Human Use, Lab Use Only.

Flubendazole is an anthelmintic drug and inhibitor of tubulin polymerization and disruption of microtubule function, also activates ATG4B, induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy.

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Biological Activity

Flubendazole is an anthelmintic drug and inhibitor of tubulin polymerization and disruption of microtubule function, also activates ATG4B, induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy.

Physicochemical Properties

M.Wt 313.29
Formula C16H12FN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl (5-(4-fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamate

References

1. Shichong Lin, et al. J Exp Clin Cancer Res. 2019 Jul 8;38(1):293.

2. Zhou X, et al. Cell Death Discov. 2018 Feb 14;4:18.

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