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Fosamprenavir calcium

Chemical Structure : Fosamprenavir calcium

CAS No.: 226700-81-8

Fosamprenavir calcium (GW-433908;GW-433908G)

Catalog No.: PC-45254Not For Human Use, Lab Use Only.

A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.

HIV Infection

Approved

Physicochemical Properties

M.Wt 623.6689
Formula C25H34CaN3O9PS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: 0.25 mg/mL (Need ultrasonic and warming); DMSO: 1.8 mg/mL

Chemical Name/SMILES

Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester, calcium salt (1:1)

References

1. Falcoz C, et al. J Clin Pharmacol. 2002 Aug;42(8):887-98.

2. Furfine ES, et al. Antimicrob Agents Chemother. 2004 Mar;48(3):791-8.

3. Wire MB, et al. AIDS. 2004 Apr 9;18(6):897-907.

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