Fremanezumab
(Anti-human CGRP mAb, human IgG2-Kappa; TEV48125)
Catalog No.: PC-Ab1047Not For Human Use, Lab Use Only.
Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene–related peptide (CGRP), a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab binds to the calcitonin gene-related peptide (CGRP) ligand, inhibiting the function of CGRP at its receptor, and thereby preventing migraine attacks..
Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene–related peptide (CGRP), a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab binds to the calcitonin gene-related peptide (CGRP) ligand, inhibiting the function of CGRP at its receptor, and thereby preventing migraine attacks.
Physicochemical Properties
M.Wt
Formula
Human IgG2-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
