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Chemical Structure : GB1874
CAS No.: 1011440-46-2
Catalog No.: PC-73231Not For Human Use, Lab Use Only.
GB1874 is an inhibitor of the Wnt pathway that targets the β-catenin-TCF4 interaction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $588 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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GB1874 is an inhibitor of the Wnt pathway that targets the β-catenin-TCF4 interaction.
GB1874 affected the proliferation and stemness of Wnt-addicted colorectal cancer (CRC) cells in vitro.
GB1874 inhibited the growth of CRC tumor xenografts in vivo.
| M.Wt | 421.559 | |
| Formula | C24H27N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-((5-((4-ethylphenoxy)methyl)-4-(1-phenylethyl)-4H-1,2,4-triazol-3-yl)thio)cyclopentan-1-one |
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1. Yannick D Benoit, et al. Cell Chem Biol. 2021 Oct 21;28(10):1394-1406.e10.
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