GBA-16-24

Chemical Structure : GBA-16-24

Catalog No.: PC-28658Not For Human Use, Lab Use Only.

GBA-16-24 is a highly potent, selective ATR inhibitor, potently disrupts cell cycle and induces apoptosis in MV-4-11 cells, more effectively inhibits cell proliferation in FLT3-mutated AML when combined with ATR inhibitors.

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Biological Activity

GBA-16-24 is a highly potent, selective ATR inhibitor, potently disrupts cell cycle and induces apoptosis in MV-4-11 cells, more effectively inhibits cell proliferation in FLT3-mutated AML when combined with ATR inhibitors.

Physicochemical Properties

M.Wt	404.44
Formula	C18H20N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5-(4-(3-methylmorpholino)-7-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)benzene-1,3-diol

References

1. Ping Li, et al. RSC Med Chem. 2026 Mar 3;17(4):2081-2095.

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GBA-16-24

Biological Activity

Physicochemical Properties

References

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