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GFH009

Chemical Structure : GFH009

CAS No.: 2247481-08-7

GFH009 (GFH 009)

Catalog No.: PC-21562Not For Human Use, Lab Use Only.

GFH009 is a potent, selective CDK9 inhibitor, inhibits the activity of the CDK9/cyclin T1 regulatory complex of P-TEFb.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GFH009 is a potent, selective CDK9 inhibitor, inhibits the activity of the CDK9/cyclin T1 regulatory complex of P-TEFb.

Physicochemical Properties

M.Wt 519.11
Formula C25H35ClN6O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[[[4-[5-Chloro-2-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino]-4-pyridinyl]-2-thiazolyl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile

References

1. Zhou F, et al. Oncotarget. 2023 Dec 20;14:997-1008.

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