Chemical Structure : GKM-001
Catalog No.: PC-49837Not For Human Use, Lab Use Only.
GKM-001 is a potent, liver-selective small molecule activator of glucokinase (GKA), demonstrates glucose lowering effect without hypoglycemia in normal and type II diabetes mellitus (T2DM).
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GKM-001 is a potent, liver-selective small molecule activator of glucokinase (GKA) with EC50 of 1.55 and 4.3 uM for human and rat GK, respectively. demonstrates glucose lowering effect without hypoglycemia in normal and type II diabetes mellitus (T2DM).
M.Wt | 580.02 | |
Formula | C25H20ClF2N3O5S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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