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GNF-1331

Chemical Structure : GNF-1331

CAS No.: 603101-22-0

GNF-1331 (GNF1331)

Catalog No.: PC-49488Not For Human Use, Lab Use Only.

GNF-1331 is a potent, selective inhibitor of Porcupine, binds to PORCN in a radioligand binding assay with IC50 of 8 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GNF-1331 is a potent, selective inhibitor of Porcupine, binds to PORCN in a radioligand binding assay with IC50 of 8 nM.

Physicochemical Properties

M.Wt 440.54
Formula C20H20N6O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(6-methoxybenzo[d]thiazol-2-yl)-2-((4-propyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide

References

1. Cheng D, et al. ACS Med Chem Lett. 2016 May 10;7(7):676-80.

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