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Chemical Structure : GNF-Pf-5660
Catalog No.: PC-61006Not For Human Use, Lab Use Only.
An antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites.
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An antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites; the digestive vacuole membrane-spanning transporter PfMDR1 is a determinant of parasite resistance to GNF-Pf-5660.
| M.Wt | 481.973 | |
| Formula | C27H28ClNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Vanaerschot M, et al. Nat Microbiol. 2017 Oct;2(10):1403-1414.
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