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GPR139 agonist 20a

Chemical Structure : GPR139 agonist 20a

CAS No.: 2983118-29-0

GPR139 agonist 20a

Catalog No.: PC-26126Not For Human Use, Lab Use Only.

GPR139 agonist 20a is a potent GPR139 agonist with EC50 of 24.7 nM, rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GPR139 agonist 20a is a potent GPR139 agonist with EC50 of 24.7 nM, rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models.

Physicochemical Properties

M.Wt 380.33
Formula C17H15F3N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-(4-oxopyrrolo[1,2-d][1,2,4]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide

References

1. Jianhang Mao, et al. J Med Chem. 2023 Oct 26;66(20):14011-14028.

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