GPR39 antagonist 61

Chemical Structure : GPR39 antagonist 61

Catalog No.: PC-26093Not For Human Use, Lab Use Only.

GPR39 antagonist 61 is a potent and selective GPR39 antagonist with pIC50 of 7.3, reduces no-reflow and infarct size in a rodent model of ischemia-reperfusion.

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Biological Activity

GPR39 antagonist 61 is a potent and selective GPR39 antagonist with pIC50 of 7.3, reduces no-reflow and infarct size in a rodent model of ischemia-reperfusion.

Physicochemical Properties

M.Wt	414.46
Formula	C21H24F2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(4,4-difluoropiperidin-1-yl)(2-(1-isopropyl-1H-pyrazol-3-yl)-4-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl)methanone

References

1. Cianciulli A, et al. ChemMedChem. 2025 Dec 16:e202500662.

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