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GRGDSP

Chemical Structure : GRGDSP

CAS No.: 91037-75-1

GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro)

Catalog No.: PC-27931Not For Human Use, Lab Use Only.

GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic hexapeptide containing the tripeptide Arg-Gly-Asp (RGD), is an integrin inhibitor and can inhibit tumor cell-adhesion to endothelial cells, significantly inhibits the proliferative response of TNCB-immune T cells in vitro.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic hexapeptide containing the tripeptide Arg-Gly-Asp (RGD), is an integrin inhibitor and can inhibit tumor cell-adhesion to endothelial cells, significantly inhibits the proliferative response of TNCB-immune T cells in vitro.

Physicochemical Properties

M.Wt 587.59
Formula C22H37N9O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Glycyl-L-arginylglycyl-L-aspartyl-L-seryl-L-proline

References

1. Cardwell MC, et al. J Cell Biol. 1988 Oct;107(4):1541-9.

2. Dejana E, et al. J Cell Biol. 1987 May;104(5):1403-11.

3. Shimo-Oka T, et al. Cell Struct Funct. 1988 Dec;13(6):515-24.

4. Ferguson TA, et al. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8072-6.

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