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Chemical Structure : GS-441524
CAS No.: 1191237-69-0
Catalog No.: PC-21077Not For Human Use, Lab Use Only.
GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $88 | In stock | |
| 200 mg | $128 | In stock | |
| 500 mg | $198 | In stock | |
| 1 g | Get quote |
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GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family.
GS-441524 effectively inhibits FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM.
| M.Wt | 291.27 | |
| Formula | C12H13N5O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
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1. Murphy BG, et al. Vet Microbiol. 2018 Jun;219:226-233.
2. Shannon A, et al. Antiviral Res. 2020 Jun;178:104793.
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