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Chemical Structure : GS-6671
Catalog No.: PC-22187Not For Human Use, Lab Use Only.
GS-6671 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 5.8 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA.
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GS-6671 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 5.8 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA.
| M.Wt | 420.89 | |
| Formula | C21H25ClN2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kato D, et al. ACS Med Chem Lett. 2024 Mar 22;15(4):546-554.
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