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GSK 163929

Chemical Structure : GSK 163929

CAS No.: 716354-04-0

GSK 163929 (GSK163929;GSK-163929)

Catalog No.: PC-61090Not For Human Use, Lab Use Only.

GSK 163929 is a potent, selective CCR5 antagonist and HIV-1 entry inhibitor with pIC50 of 8.37 and 8.46 in HOS and PBL assays, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK 163929 is a potent, selective CCR5 antagonist and HIV-1 entry inhibitor with pIC50 of 8.37 and 8.46 in HOS and PBL assays, respectively.

    Physicochemical Properties

    M.Wt 696.255
    Formula C36H40ClF2N5O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-chloro-2-fluoro-5-(4-(3-fluorophenyl)-4-(2-((1R,3r,5S)-3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)piperidine-1-carbonyl)-N-methylbenzenesulfonamide

    References

    1. Kazmierski WM, et al. J Med Chem. 2011 Jun 9;54(11):3756-67.

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