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GSK251

Chemical Structure : GSK251

CAS No.: 2125968-05-8

GSK251 (GSK 251)

Catalog No.: PC-72781Not For Human Use, Lab Use Only.

GSK251 is a highly potent, selective, orally bioavailable inhibitor of PI3Kδ with pKi of 10.9, >1,000-fold selectivity over other PI3K isoforms.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK251 is a highly potent, selective, orally bioavailable inhibitor of PI3Kδ with pKi of 10.9, >1,000-fold selectivity over other PI3K isoforms.

Physicochemical Properties

M.Wt 584.711
Formula C29H37FN6O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
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Solubility

Chemical Name/SMILES

References

1. Kenneth Down, et al. J. Med. Chem. 2021, 64, 18, 13780–13792.

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