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GSK3527497

Chemical Structure : GSK3527497

CAS No.: 2215855-22-2

GSK3527497 (GSK-3527497)

Catalog No.: PC-73096Not For Human Use, Lab Use Only.

GSK3527497 (GSK-3527497) is a potent, selective TRPV4 inhibitor with IC50 of 12 nM (hTRPV4).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK3527497 (GSK-3527497) is a potent, selective TRPV4 inhibitor with IC50 of 12 nM (hTRPV4).
GSK3527497 is a pre-clinical candidate for treatment of diseases resulting from TRPV4 activation.

Physicochemical Properties

M.Wt 426.847
Formula C17H16ClFN4O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Carl A Brooks, et al. J Med Chem. 2019 Oct 24;62(20):9270-9280.

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