You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-DNA Methyltransferase (DNMT)-GSK3543105
GSK3543105

Chemical Structure : GSK3543105

CAS No.: 2170139-57-6

GSK3543105 (GSK 3543105)

Catalog No.: PC-73377Not For Human Use, Lab Use Only.

GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

Packing Price Stock Quantity
25 mg Get quote
100 mg Get quote
200 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

Physicochemical Properties

M.Wt 464.588
Formula C24H28N6O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((3,5-dicyano-4-ethyl-6-(4-(2-hydroxyethyl)-1,4-diazepan-1-yl)pyridin-2-yl)thio)-2-phenylacetamide

References

1. Horton JR, et al. Structure. 2022 Mar 28:S0969-2126(22)00090-9.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: