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GSK4394835A

Chemical Structure : GSK4394835A

CAS No.: 3032458-06-0

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GSK4394835A (GSK4394835)

Catalog No.: PC-25896Not For Human Use, Lab Use Only.

GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

    Physicochemical Properties

    M.Wt 499.33
    Formula C27H26BN3O6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3-(Benzyl(methyl)carbamoyl)-5-(4,7-dimethoxyquinoline-2-carboxamido)phenyl)boronic Acid

    References

    1. Eaton SA, et al. J Med Chem. 2025 Dec 2. doi: 10.1021/acs.jmedchem.5c03081.

    2. Rowley AM, et al. J Med Chem. 2024 Feb 8;67(3):2049-2065.

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