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GSK4716

Chemical Structure : GSK4716

CAS No.: 101574-65-6

GSK4716 (GSK 4716)

Catalog No.: PC-20415Not For Human Use, Lab Use Only.

GSK4716 (GSK 4716) is a selective agonist of estrogen-related receptors ERRβ and ERRγ with EC50 of 1.3 uM (ERRγ).

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Biological Activity

GSK4716 (GSK 4716) is a selective agonist of estrogen-related receptors ERRβ and ERRγ with EC50 of 1.3 uM (ERRγ).
GSK4716 displays selectivity over ERRα and the classical estrogen receptors.

Physicochemical Properties

M.Wt 282.34
Formula C17H18N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide

References

1. Zuercher WJ, et al. J Med Chem. 2005 May 5;48(9):3107-9.

2. Krid H, et al. PLoS One. 2012;7(3):e34223.

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