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Chemical Structure : GSK717
CAS No.: 1595278-21-9
Catalog No.: PC-38557Not For Human Use, Lab Use Only.
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $138 | In stock | |
| 25 mg | $238 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
| M.Wt | 452.55 | |
| Formula | C28H28N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-[2-(Benzoylmethylamino)ethyl]-N-(2,3-dihydro-1H-inden-5-yl)-1H-benzimidazole-1-acetamide |
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1. Rickard DJ, et al. PLoS One. 2013 Aug 1;8(8):e69619.
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