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Chemical Structure : GSK805
CAS No.: 1426802-50-7
Catalog No.: PC-43201Not For Human Use, Lab Use Only.
GSK805 is a potent, orally bioavailable, CNS penetrant RORγt inhibitor with pIC50 of 8.5 and 8.0 in FRET and Th17 assays, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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GSK805 is a potent, orally bioavailable, CNS penetrant RORγt inhibitor with pIC50 of 8.5 and 8.0 in FRET and Th17 assays, respectively。
GSK805 demonstrates excellent in vivo efficacy in EAE mice dose dependently.
| M.Wt | 532.3596 | |
| Formula | C23H18Cl2F3NO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzeneacetamide, N-[2,6-dichloro-2'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]-4-(ethylsulfonyl)- |
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1. Wang Y, et al. ACS Med Chem Lett. 2015 May 26;6(7):787-92.
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