Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Bacterial-GSK951A
GSK951A

Chemical Structure : GSK951A

CAS No.: 1403602-33-4

Add to Favorites

GSK951A (GSK-951A)

Catalog No.: PC-61005Not For Human Use, Lab Use Only.

GSK951A is a small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM, targets enoyl-coenzyme A (CoA) hydratase EchA6 with binding Kd of 0.45 uM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK951A is a small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM, targets enoyl-coenzyme A (CoA) hydratase EchA6 with binding Kd of 0.45 uM.
    GSK951A suppresses mycolic acid synthesis and EchA6 is essential, and are bactericidal in mouse model of chronic tuberculosis infection.

    Physicochemical Properties

    M.Wt 472.468
    Formula C24H23F3N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (5R,7S)-N-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(4-ethylphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

    References

    1. Cox JA, et al. Nat Microbiol. 2016 Jan 18;1:15006.

    2. Remuiñán MJ, et al. PLoS One. 2013 Apr 17;8(4):e60933.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: