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Chemical Structure : GSTO1 inhibitor C1-27
CAS No.: 568544-03-6
Catalog No.: PC-61194Not For Human Use, Lab Use Only.
GSTO1 inhibitor C1-27 is a potent, selective, covalent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.
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|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $228 | In stock | |
| 50 mg | $368 | In stock | |
| 100 mg | Get quote |
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GSTO1 inhibitor C1-27 is a potent, selective, covalent glutathione S-transferase omega 1 (GSTO1) inhibitor with IC50 of 31 nM.
GSTO1 inhibitor C1-27 displays selective inhibition of the GSTO1 against several other cysteine-containing proteins at 1 uM.
GSTO1 inhibitor C1-27 suppresses cancer cell growth, enhances the cytotoxic effects of cisplatin and inhibits tumour growth in colon cancer models as single agent.
| M.Wt | 311.177 | |
| Formula | C10H12Cl2N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)acetamide |
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1. Ramkumar K, et al. Nat Commun. 2016 Oct 5;7:13084.
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