Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GW311616A
Catalog No.: PC-49568Not For Human Use, Lab Use Only.
GW311616A is a potent, specifc intracellular and orally active inhibitor of human neutrophil elastase (HNE) with Ki of 0.31 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GW311616A is a potent, specifc intracellular and orally active inhibitor of human neutrophil elastase (HNE) with Ki of 0.31 nM.
GW311616A significantly reduced injury-induced neointimal hyperplasia (NIH) in both neutrophil elastase-deficient mice and mice.
GW311616A reversed insulin resistance and body weight gain in HFD-fed mice.
| M.Wt | 397.53 | |
| Formula | C19H31N3O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Macdonald SJ, et al. Bioorg Med Chem Lett. 2001 Apr 9;11(7):895-8.
2. Mansuy-Aubert V, et al. Cell Metab. 2013 Apr 2;17(4):534-48.
3. Mei Yang, et al. Br J Pharmacol. 2021 Oct;178(20):4048-4068.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
