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GYKI-53655

Chemical Structure : GYKI-53655

CAS No.: 143692-48-2

GYKI-53655 (GYKI 53655 hydrochloride, LY300168)

Catalog No.: PC-27552Not For Human Use, Lab Use Only.

GYKI-53655 (GYKI 53655, LY300168) is a non-competitive AMPA receptor antagonist with IC50 of 5.9 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GYKI-53655 (GYKI 53655, LY300168) is a non-competitive AMPA receptor antagonist with IC50 of 5.9 uM.

Physicochemical Properties

M.Wt 388.85
Formula C19H21ClN4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-7H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepine-7-carboxamide hydrochloride

References

1. Partin KM, et al. Mol Pharmacol. 1996 Jan;49(1):142-8.

2. Nooney JM, et al. Br J Pharmacol. 1995 Feb;114(3):648-55.

3. Palmer AJ, et al. Eur J Pharmacol. 1993 Jan 15;244(2):193-4.

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