Catalog No.: PC-62558Not For Human Use, Lab Use Only.
Garcinol (Camboginol) is a potent, natural inhibitor of histone acetyltransferases (HATs) p300 (IC50=7 uM) and PCAF (IC50=5 uM) both in vitro and in vivo.
Garcinol (Camboginol) is a potent, natural inhibitor of histone acetyltransferases (HATs) p300 (IC50=7 uM) and PCAF (IC50=5 uM) both in vitro and in vivo.
Garcinol (Camboginol) downregulates various cell survival proteins including survivin, bcl-2, XIAP, and cFLIP, and induces bid cleavage, bax, and cytochrome c release.
Garcinol (Camboginol) potentiates TRAIL-induced apoptosis through upregulation of death receptors and downregulation of antiapoptotic proteins.
Garcinol (Camboginol) also siimulates neurogenesis and ex vivo expansion of human hematopoietic stem cells.
