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Gemcitabine

Chemical Structure : Gemcitabine

CAS No.: 95058-81-4

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Gemcitabine (LY 188011;NSC 613327;LY188011;LY-188011)

Catalog No.: PC-45149Not For Human Use, Lab Use Only.

Gemcitabine (NSC 613327, LY188011) is a synthetic pyrimidine nucleoside prodrug that works by ihibiting the enzyme ribonucleotide reductase (RNR) and blocking the creation of new DNA.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Gemcitabine (NSC 613327, LY188011) is a synthetic pyrimidine nucleoside prodrug that works by ihibiting the enzyme ribonucleotide reductase (RNR) and blocking the creation of new DNA.
Gemcitabine is a chemotherapy agent for treatment of a number of types of cancer.

Physicochemical Properties

M.Wt 263.1982
Formula C9H11F2N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Cytidine, 2'-deoxy-2',2'-difluoro-

References

1. Wang H, et al. Anticancer Res. 2011 Oct;31(10):3171-80.

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