Chemical Structure : Globomycin
CAS No.:
67076-74-8
Globomycin
Catalog No.: PC-23142Not For Human Use, Lab Use Only.
Globomycin is a cyclic depsipeptide antibiotic, specific inhibitor of the prolipoprotein signal peptidase, inhibits the essential type II signal peptidase prolipoprotein signal peptidase (LspA), shows antimicrobial effect against Gram-negative bacteria.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Globomycin is a cyclic depsipeptide antibiotic, specific inhibitor of the prolipoprotein signal peptidase, inhibits the essential type II signal peptidase prolipoprotein signal peptidase (LspA), shows antimicrobial effect against Gram-negative bacteria.
Physicochemical Properties
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M.Wt
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655.82
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Formula
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C32H57N5O9
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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Cyclo[L-alloisoleucyl-L-seryl-L-allothreonylglycyl-(2R,3R)-3-hydroxy-2-methylnonanoyl-N-methyl-L-leucyl]
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References
1. Inukai M, et al. J Bacteriol. 1979 Dec;140(3):1098-101.
2. Nakajima M, et al. J Antibiot (Tokyo). 1978 May;31(5):426-32.
3. Tokunaga M, et al. J Biol Chem. 1983 Oct 25;258(20):12102-5.
4. Tokunaga M, et al. Proc Natl Acad Sci U S A. 1982 Apr;79(7):2255-9.
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