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Gossypetin

Chemical Structure : Gossypetin

CAS No.: 489-35-0

Gossypetin

Catalog No.: PC-28335Not For Human Use, Lab Use Only.

Gossypetin is a hexahydroxylated flavonoid within antioxidant, antibacterial and anticancer activities, is a potent inhibitor of MKK3 and MKK6, also is a USP5-Cav3.2 disruptor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Gossypetin is a hexahydroxylated flavonoid within antioxidant, antibacterial and anticancer activities, is a potent inhibitor of MKK3 and MKK6, also is a USP5-Cav3.2 disruptor.
Gossypetin ameliorates ionizing radiation-induced oxidative stress in mice liver
Gossypetin reverses inflammatory and neuropathic pain.
Gossypetin induces G2 phase arrest and apoptosis of esophageal cancer cells.
Gossypetin suppresses esophageal cancer growth in vitro and in vivo.

Physicochemical Properties

M.Wt 318.24
Formula C15H10O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-chromen-4-one

References

1. Rankin SM, et al. Biochem Pharmacol. 1993 Jan 7;45(1):67-75.

2. Khan A, et al. Free Radic Res. 2015 Oct;49(10):1173-86.

3. Gadotti VM, et al. Mol Pain. 2015 Mar 14;11:12.

4. Xie X, et al. Cancer Lett. 2019 Feb 1;442:126-136.

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