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Chemical Structure : Gunagratinib
Catalog No.: PC-38396Not For Human Use, Lab Use Only.
ICP-192 (Gunagratinib) is a novel potent, covalent pan-FGFR (fibroblast growth factor receptors) inhibitor, potently and selectively inhibits FGFR activities irreversibly by covalent binding.
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ICP-192 (Gunagratinib) is a novel potent, covalent pan-FGFR (fibroblast growth factor receptors) inhibitor, potently and selectively inhibits FGFR activities irreversibly by covalent binding.
ICP-192 (Gunagratinib) overcomes the acquired resistance to the first-generation reversible FGFR inhibitors, e.g., infigratinib.
| M.Wt | 423.473 | |
| Formula | C22H25N5O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ye Guo, et al. 2021 ASCO Annual Meeting I.
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