You are here:Home-Chemical Inhibitors & Agonists-Immunology/Inflammation-PGE synthase-H-PGDS inhibitor 1y
H-PGDS inhibitor 1y

Chemical Structure : H-PGDS inhibitor 1y

CAS No.: 2255311-93-2

H-PGDS inhibitor 1y

Catalog No.: PC-49637Not For Human Use, Lab Use Only.

H-PGDS inhibitor 1y is a potent peripherally restricted H-PGDS inhibitor with IC50 of 9.4 nM, compound 1y is efficacious in four in vivo inflammatory models and exhibits no CNS toxicity.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

H-PGDS inhibitor 1y is a potent peripherally restricted H-PGDS inhibitor with IC50 of 9.4 nM, compound 1y is efficacious in four in vivo inflammatory models and exhibits no CNS toxicity.

Physicochemical Properties

M.Wt 353.47
Formula C21H27N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-cyclopropyl-N-((1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl)-1,8-naphthyridine-3-carboxamide

References

1. Rodolfo Cadilla, et al. Bioorg Med Chem. 2020 Dec 1;28(23):115791.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: