H135

Chemical Structure : H135

Catalog No.: PC-25730Not For Human Use, Lab Use Only.

H35 is a potent and selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 12.7 nM, exerts broad anti-SARS-CoV-2 activity.

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Biological Activity

H35 is a potent and selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 12.7 nM, exerts broad anti-SARS-CoV-2 activity.

M.Wt	559.56
Formula	C25H33F4N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,4R)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-2-cyclohexyl-2-(1-fluorocyclopropane-1-carboxamido)acetyl)-4-(trifluoromethoxy)pyrrolidine-2-carboxamide

1. Yuan S, et al. J Virol. 2025 Nov 14:e0100125.