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Chemical Structure : H3B-968
CAS No.: 2912294-90-5
Catalog No.: PC-21006Not For Human Use, Lab Use Only.
H3B-968 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 41 and 13 nM in ADP-Glo assay DNA unwinding assay, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $278 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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H3B-968 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 41 and 13 nM in ADP-Glo assay DNA unwinding assay, respectively.
| M.Wt | 548.46 | |
| Formula | C22H18F6N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(4-ethylphenyl)-2-((4-(4-(trifluoromethoxy)phenyl)-6-(trifluoromethyl)pyrimidine)-2-sulfonamido)acetamide |
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1. Mackenzie J Parker, et al. Biochemistry. 2023 Jul 18;62(14):2147-2160.
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